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Á¦¸ñ The Diagnosis of Leprosy by te Sternal Puncture
ÀúÀÚ Shi Ryong Choi ¼Ò¼Ó
³âµµ 1963 ±Ç 2
È£ 1 ¹øÈ£
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¿ä¾à The author examined 200 patients with leprosy (Hansen's Disease) using one of the
new methods of saponin concentration with the following results:
1. The bone marrow obtained by sternal puncture was allowed to stand 24 hrs at
room temperature. The leucocyte layer on top and the suspension layer were examined.
More leprosy bacilli were found in the suspension layer than from the leucocyte layer.
2. When an antiformin concentration method was used the number of leprosy bacilli
found was not increase.
3. Using the saponin concentration method leprosy bacilli were found 91% of patients
of the tuberculoid type, 71% of the lepromatous type and in 3 out of 10 cases of
maculo-anaesthetic leprosy.
4. Sodium iodide was administered to 20 patients in whose bone marrow no leprosy
bacilli had been found. When the symptoms recurred the, bone marrow was again
examined with the finding of only one positive case out of the 20 patients.
5. The percentage leprosy patients in whom bacilli were found in bone marrow was
highest in cases of the lepromatous type, next highest in cases of the tuberculoid type
and lowest in the inaculoanaesthetic type.
There was no correlation between the percentage of discovery rate and the clinical
severity of the disease.
6. There was no correlation between the percentage positive cases discovered and the
duration of illness. There seemed to be a higher percentage in the early years (0-4
years) in the lepromatous type.
7. The rate of discovery of bacilli was higher in little treated than in patients who
had received more treatment.
8. The rate of discovery of leprosy bacilli was high bone marrow examination in all
types of leprosy and even higher when treated with saponin and concentrated.
The saponin method of detection of leprosy bacilli seems to be of value in the
diagnosis of leprosy especially in the early swage.
It is also of value in providing information regarding the presence of leprosy bacilli in
the body.
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